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1

Differential utilization of ketone bodies by neurons and glioma cell lines: a rationale for ketogenic diet as experimental glioma therapy

Gabriele D Maurer, Daniel P Brucker, Oliver Bähr, Patrick N Harter, Elke Hattingen, Stefan Walenta, Wolfgang Mueller-Klieser, Joachim P Steinbach, Johannes Rieger

Journal:

Year:

2011

Language:

english

File:

PDF, 773 KB

english, 2011

2

Test System for Trifunctional Antibodies in 3D MCTS Culture

Hirschhaeuser, F., Leidig, T., Rodday, B., Lindemann, C., Mueller-Klieser, W.

Journal:

Journal of Biomolecular Screening

Year:

2009

Language:

english

File:

PDF, 752 KB

english, 2009

3

Three-dimensional cell culture induces novel proliferative and metabolic alterations associated with oncogenic transformation

Leoni A. Kunz-Schughart, Karlfried Groebe, Wolfgang Mueller-Klieser

Journal:

International Journal of Cancer

Year:

1996

Language:

english

File:

PDF, 1.15 MB

english, 1996

4

Semiquantitative bioluminescent assay of glutathione

Francisco J. Romero, Wolfgang Mueller-Klieser

Journal:

Year:

1998

Language:

english

File:

PDF, 56 KB

english, 1998

5

Endothelial capillaries chemotactically attract tumour cells

Cornelie von Bülow, Wiebke Hayen, Anke Hartmann, Wolfgang Mueller-Klieser, Bruno Allolio, Volker Nehls

Journal:

The Journal of Pathology

Year:

2001

Language:

english

File:

PDF, 343 KB

english, 2001

6

Biological response of multicellular emt6 spheroids to exogenous lactate

B. Bourrat-Floeck, K. Groebe, W. Mueller-Klieser

Journal:

International Journal of Cancer

Year:

1991

Language:

english

File:

PDF, 908 KB

english, 1991

7

Relation between autoradiographically measured blood flow and ATP concentrations obtained from imaging bioluminescence in tumors following hyperthermia

Marc Dellian, Stefan Walenta, Gerhard E. H. Kuhnle, Fernando Gamarra, Wolfgang Mueller-Klieser, Alwin E. Goetz

Journal:

International Journal of Cancer

Year:

1993

Language:

english

File:

PDF, 866 KB

english, 1993

8

Calibration of misonidazole labeling by simultaneous measurement of oxygen tension and labeling density in multicellular spheroids

Markus W. Gross, Ulrich Karbach, Karlfried Groebe, Allan J. Franko, Wolfgang Mueller-Klieser

Journal:

International Journal of Cancer

Year:

1995

Language:

english

File:

PDF, 1.14 MB

english, 1995

9

Growth-related changes of oxygen consumption rates of tumor cells grown in vitro and in vivo

F. Kallinowski, G. Tyler, W. Mueller-Klieser, P. Vaupel

Journal:

Journal of Cellular Physiology

Year:

1989

Language:

english

File:

PDF, 950 KB

english, 1989

10

Proliferation-associated oxygen consumption and morphology of tumor cells in monolayer and spheroid culture

A. Bredel-Geissler, U. Karbach, S. Walenta, L. Vollrath, W. Mueller-Klieser

Journal:

Journal of Cellular Physiology

Year:

1992

Language:

english

File:

PDF, 978 KB

english, 1992

11

Intracapillary oxyhemoglobin saturation of malignant tumors in humans

Wolfgang Mueller-Klieser, Peter Vaupel, Rolf Manz, Ralf Schmidseder

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

1981

Language:

english

File:

PDF, 735 KB

english, 1981

12

Cellular growth and metabolic adaptations to nutrient stress environments in tumor microregions

R. Sutherland, J. Freyer, W. Mueller-Klieser, R. Wilson, C. Heacock, J. Sciandra, B. Sordat

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

1986

File:

PDF, 471 KB

1986

13

Improvement of tumor spheroid oxygenation by Tetrachlorodecaoxide

Wolfgang Mueller-Klieser, Peter Vaupel

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

1987

Language:

english

File:

PDF, 775 KB

english, 1987

14

Lactate-induced inhibition of tumor cell proliferation

E. Marx, W. Mueller-Klieser, P. Vaupel

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

1988

Language:

english

File:

PDF, 705 KB

english, 1988

15

On the relation between size of necrosis and diameter of tumor spheroids

Karlfried Groebe, Wolfgan Mueller-Klieser

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

1996

Language:

english

File:

PDF, 745 KB

english, 1996

16

Multicellular tumor spheroids: An underestimated tool is catching up again

Franziska Hirschhaeuser, Heike Menne, Claudia Dittfeld, Jonathan West, Wolfgang Mueller-Klieser, Leoni A. Kunz-Schughart

Journal:

Journal of Biotechnology

Year:

2010

Language:

english

File:

PDF, 1.29 MB

english, 2010

17

Tissue gradients of energy metabolites mirror oxygen tension gradients in a rat mammary carcinoma model

M.W. Dewhirst, S. Walenta, S. Snyder, W. Mueller-Klieser, R. Braun, B. Chance

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2000

Language:

english

File:

PDF, 241 KB

english, 2000

18

Elevated tumor lactate concentrations predict for an increased risk of metastases in head-and-neck cancer

David M Brizel, Thies Schroeder, Richard L Scher, Stefan Walenta, Robert W Clough, Mark W Dewhirst, Wolfgang Mueller-Klieser

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2001

Language:

english

File:

PDF, 87 KB

english, 2001

19

Tissue gradients of energy metabolites mirror oxygen tension gradients in a rat mammary carcinoma model

Stefan Walenta, Stacey Snyder, Zishan A Haroon, Rod D Braun, Khalid Amin, David Brizel, Wolfgang Mueller-Klieser, Britton Chance, Mark W Dewhirst

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2001

Language:

english

File:

PDF, 767 KB

english, 2001

20

Glucose processing may be rate limiting step in R3230Ac mammary carcinoma metabolism

M.W. Dewhirst, B. Klitzman, S. Ettinger, C. Poellman, J. Poulson, S. Snyder, W. Mueller-Klieser, S. Walenta, J. Biaglow

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2001

Language:

english

File:

PDF, 50 KB

english, 2001

21

In regard to tarnawski et al., IJROBP 2002;52:1271–1276

Stefan Walenta, Thies Schroeder, Wolfgang Mueller-Klieser

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2002

Language:

english

File:

PDF, 21 KB

english, 2002

22

Tumor biology and experimental therapeutics

Wolfgang Mueller-Klieser

Journal:

Critical Reviews in Oncology/Hematology

Year:

2000

Language:

english

File:

PDF, 1.22 MB

english, 2000

23

Metabolic mapping with bioluminescence: basic and clinical relevance

Stefan Walenta, Thies Schroeder, Wolfgang Mueller-Klieser

Journal:

Biomolecular Engineering

Year:

2002

Language:

english

File:

PDF, 718 KB

english, 2002

24

High-resolution histographical mapping of glucose concentrations in developing cotyledons ofVicia fabain relation to mitotic activity and storage processes: glucose as a possible developmental trigger

Ljudmilla Borisjuk, Stefan Walenta, Hans Weber, Wolfgang Mueller-Klieser, Ulrich Wobus

Journal:

The Plant Journal

Year:

1998

Language:

english

File:

PDF, 431 KB

english, 1998

25

Spatial analysis of plant metabolism: Sucrose imaging within Vicia faba cotyledons reveals specific developmental patterns

Ljudmilla Borisjuk, Stefan Walenta, Hardy Rolletschek, Wolfgang Mueller-Klieser, Ulrich Wobus, Hans Weber

Journal:

The Plant Journal

Year:

2002

Language:

english

File:

PDF, 366 KB

english, 2002

26

Geographical mapping of metabolites in biological tissue with quantitative bioluminescence and single photon imaging

W. Mueller-Klieser, S. Walenta

Journal:

Journal of Molecular Histology

Year:

1993

Language:

english

File:

PDF, 8.32 MB

english, 1993

27

Distributions of oxygen, nutrient, and metabolic waste concentrations in multicellular spheroids and their dependence on spheroid parameters

K. Groebe, W. Mueller-Klieser

Journal:

European Biophysics Journal

Year:

1991

Language:

english

File:

PDF, 1.13 MB

english, 1991

28

Influence of growth, measuring conditions, and cell types on oxygen tensions in multicell tumor spheroids determined by microelectrodes

W. F. Mueller-Klieser, R. M. Sutherland

Journal:

Radiation and Environmental Biophysics

Year:

1981

Language:

english

File:

PDF, 77 KB

english, 1981

29

Mapping and quantification of biomolecules in tumor biopsies using bioluminescence

G. Schwickert, S. Walenta, W. Mueller-Klieser

Journal:

Cellular and Molecular Life Sciences

Year:

1996

Language:

english

File:

PDF, 558 KB

english, 1996

30

Impact of Hypoxia and the Metabolic Microenvironment on Radiotherapy of Solid Tumors

Daniel Zips, Markus Adam, Michael Flentje, Axel Haase, Michael Molls, Wolfgang Mueller-Klieser, Cordula Petersen, Christine Philbrook, Peter Schmitt, Oliver Thews, Stefan Walenta, Michael Baumann

Journal:

Strahlentherapie und Onkologie

Year:

2004

File:

PDF, 502 KB

2004

31

Laktat und Redoxstatus in malignen Tumoren

U.G.A. Sattler, S. Walenta, W. Mueller-Klieser

Journal:

Der Anaesthesist

Year:

2007

Language:

german

File:

PDF, 949 KB

german, 2007

32

Efficacy of catumaxomab in tumor spheroid killing is mediated by its trifunctional mode of action

Franziska Hirschhaeuser, Stefan Walenta, Wolfgang Mueller-Klieser

Journal:

Cancer Immunology, Immunotherapy

Year:

2010

Language:

english

File:

PDF, 422 KB

english, 2010

33

Tumor cell migration is not influenced by p21 in colon carcinoma cell lines after irradiation with X-ray or12C heavy ions

Kristina Goetze, Michael Scholz, Gisela Taucher-Scholz, Wolfgang Mueller-Klieser

Journal:

Radiation and Environmental Biophysics

Year:

2010

Language:

english

File:

PDF, 395 KB

english, 2010

34

Metabolic classification of human rectal adenocarcinomas: a novel guideline for clinical oncologists?

Stefan Walenta, The-Van Chau, Thies Schroeder, Hans-Anton Lehr, Leoni A. Kunz-Schughart, Alois Fuerst, Wolfgang Mueller-Klieser

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

2003

Language:

english

File:

PDF, 736 KB

english, 2003

35

Metabolic and proteomic differentials in head and neck squamous cell carcinomas and normal gingival tissue

Thomas Ziebart, Stefan Walenta, Martin Kunkel, Torsten E. Reichert, Wilfried Wagner, Wolfgang Mueller-Klieser

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

2011

Language:

english

File:

PDF, 508 KB

english, 2011

36

Protein profiles in human ovarian cancer cell lines correspond to their metabolic activity and to metabolic profiles of respective tumor xenografts

Christian Fabian, Lisa Koetz, Elena Favaro, Stefano Indraccolo, Wolfgang Mueller-Klieser, Ulrike G. A. Sattler

Journal:

Year:

2012

Language:

english

File:

PDF, 467 KB

english, 2012

37

Pixel-to-pixel correlation between images of absolute ATP concentrations and blood flow in tumours

Walenta, S, Dellian, M, Goetz, AE, Kuhnle, GEH, Mueller-Klieser, W

Journal:

British Journal of Cancer

Year:

1992

Language:

english

File:

PDF, 1.23 MB

english, 1992

38

A bioluminescence technique for quantitative and structure-associated imaging of pyruvate

Sattler, Ulrike G A, Walenta, Stefan, Mueller-Klieser, Wolfgang

Journal:

Laboratory Investigation

Year:

2006

Language:

english

File:

PDF, 349 KB

english, 2006

39

Multicellular spheroids

Wolfgang Mueller-Klieser

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

1987

Language:

english

File:

PDF, 3.09 MB

english, 1987

40

Regional determination of ATP, glucose and lactate in cervical-cancer biopsies

G. Schwickert, S. Walenta, W. Mueller-Klieser, E. K. Rofstad

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

1995

Language:

english

File:

PDF, 169 KB

english, 1995

41

Effects of three modifiers of glycolysis on ATP, lactate, hypoxia, and growth in human tumor cell lines in vivo

A. Yaromina, S. Meyer, C. Fabian, K. Zaleska, U.G.A. Sattler, L.A. Kunz-Schughart, W. Mueller-Klieser, D. Zips, M. Baumann

Journal:

Strahlentherapie und Onkologie

Year:

2012

Language:

english

File:

PDF, 741 KB

english, 2012

42

Lactate: mirror and motor of tumor malignancy

Stefan Walenta, Wolfgang F Mueller-Klieser

Journal:

Seminars in Radiation Oncology

Year:

2004

Language:

english

File:

PDF, 282 KB

english, 2004

43

Lactate adversely affects the in vitro formation of endothelial cell tubular structures through the action of TGF-β1

Stephan A. Schmid, Andreas Gaumann, Marit Wondrak, Christoph Eckermann, Stephanie Schulte, Wolfgang Mueller-Klieser, Denys N. Wheatley, Leoni A. Kunz-Schughart

Journal:

Experimental Cell Research

Year:

2007

Language:

english

File:

PDF, 2.19 MB

english, 2007

44

Mapping of metabolites in biological tissues with bioluminescence

S Walenta, W Mueller-Klieser

Journal:

Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology

Year:

1999

Language:

english

File:

PDF, 154 KB

english, 1999

45

Oxygen profile of microencapsulated islets: effect of immobilised hemoglobin in the alginate matrix

J Schrezenmeir, A Hyder, M Vreden, C Laue, W Mueller-Klieser

Journal:

Transplantation Proceedings

Year:

2001

Language:

english

File:

PDF, 394 KB

english, 2001

46

Hypoxia Inducible Factor-1α Inactivation Unveils a Link between Tumor Cell Metabolism and Hypoxia-Induced Cell Death

Elena Favaro, Giorgia Nardo, Luca Persano, Massimo Masiero, Lidia Moserle, Rita Zamarchi, Elisabetta Rossi, Giovanni Esposito, Mario Plebani, Ulrike Sattler, Thomas Mann, Wolfgang Mueller-Klieser, Vin

Journal:

The American Journal of Pathology

Year:

2008

Language:

english

File:

PDF, 1.44 MB

english, 2008

47

Three-dimensional Invasion of Human Glioblastoma Cells Remains Unchanged by X-ray and Carbon Ion Irradiation In Vitro

Iris Eke, Katja Storch, Ina Kästner, Anne Vehlow, Christina Faethe, Wolfgang Mueller-Klieser, Gisela Taucher-Scholz, Achim Temme, Gabriele Schackert, Nils Cordes

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2012

Language:

english

File:

PDF, 1.65 MB

english, 2012

48

Tumor lactate content predicts for response to fractionated irradiation of human squamous cell carcinomas in nude mice

Verena Quennet, Ala Yaromina, Daniel Zips, Andrea Rosner, Stefan Walenta, Michael Baumann, Wolfgang Mueller-Klieser

Journal:

Radiotherapy and Oncology

Year:

2006

Language:

english

File:

PDF, 406 KB

english, 2006

49

Glycolytic metabolism and tumour response to fractionated irradiation

Ulrike G.A. Sattler, Sandra S. Meyer, Verena Quennet, Christian Hoerner, Hannah Knoerzer, Christian Fabian, Ala Yaromina, Daniel Zips, Stefan Walenta, Michael Baumann, Wolfgang Mueller-Klieser

Journal:

Radiotherapy and Oncology

Year:

2010

Language:

english

File:

PDF, 567 KB

english, 2010

50

Inhibition of tumor lactate oxidation: Consequences for the tumor microenvironment

Morten Busk, Stefan Walenta, Wolfgang Mueller-Klieser, Torben Steiniche, Steen Jakobsen, Michael Robert Horsman, Jens Overgaard

Journal:

Radiotherapy and Oncology

Year:

2011

Language:

english

File:

PDF, 1.90 MB

english, 2011

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